Biologe (m/w/d)

Universität Bonn

53127 Bonn - Deutschland

Biologe/Biologin Arbeit Vollzeit ab 24.09.2025

Beschreibung

The Institute of Molecular Medicine and Experimental Immunology (IMMEI), located at the Medical Faculty Campus of Bonn University Clinic, provides an exceptional environment for cutting-edge research. Our state-of-the-art facilities offer a platform for collaboration and innovation. The working group is led by Prof. Dr. Zeinab Abdullah (https://www.immei.de/research/zeinab-abdullah-laboratory), who has substantial experience and expertise in the field. Her position within the local and global scientific community and her expertise provides a valuable opportunity to make significant contributions to the scientific literature. The project will be co-supervised by Dr. Dillon Corvino a senior post-doctoral researcher, with expertise in in vitro and in vivo techniques and bioinformatics analysis. The project will be carried out within the framework and context of the Immunosensation Cluster of Excellence (https://dev.bestviews.de/tour/uni-klinik-bonn/progress/4.0/#popup_3140).
Project description:
Hepatic NK-like T cells represent a diverse and enigmatic subset within the liver immune milieu. Despite their potential significance in immune regulation and therapeutic intervention, much about their biology remains elusive. Recent research conducted by our collaborative team has identified a novel population of NK-like T cells termed NLCs in both mice and humans. During viral infection or immune activation, NLCs exhibit multifaceted functional profiles, including T helper-like, cytotoxic, and innate lymphocyte functions. In this project, we will investigate their development and the underlying mechanisms of their effector functions.
Design and execute experiments
Stay current with relevant literature and contribute ideas to research project
Analyse data and generate publication-quality figures
Present results in lab meetings and national/international conferences
Contribute to manuscript preparation

FELASA B certification (or equivalent) qualification for animal work
Murine (in vivo) experience
Experience with processing and handling of human samples
Proficiency in flow cytometry (conventional and/or spectral)
Experience with molecular biology techniques
Tissue culture experience
Familiarity with T cell and/or NK cell biology
Experience with bioinformatics (R or Python)

Competitive salary according to the German salary scale TV-L E13 65%.
National and International collaboration
Opportunity to contribute to cutting-edge research with real-world implications.
Access to state-of-the-art facilities and resources.
Extensive training opportunities

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