TRON -Translationale Onkologie an der Universitätsmedizin der JGU Mainz gemeinnützige G...
55131 Mainz am Rhein - Deutschland
Biologisch-technische/r Assistent/in
Arbeit
Vollzeit
ab 07.01.2026
Beschreibung
We are looking for support in our Single-Cell Omics unit to start as soon as possible as parental leave replacement. The successful candidate will be working with patient biopsies, cell lines and murine tissue samples to support the establishment and apply state-of-the-art multiomic single cell sequencing methods and immunoassays to contribute to the development of novel immunotherapies against cancer and other diseases.
Process primary samples (healthy donor and patient tissues), including ha... weiter lesen
Process primary samples (healthy donor and patient tissues), including ha... weiter lesen
We are looking for support in our Single-Cell Omics unit to start as soon as possible as parental leave replacement. The successful candidate will be working with patient biopsies, cell lines and murine tissue samples to support the establishment and apply state-of-the-art multiomic single cell sequencing methods and immunoassays to contribute to the development of novel immunotherapies against cancer and other diseases.
Process primary samples (healthy donor and patient tissues), including handling of fresh, cryopreserved, or fixed material and tissue dissociation
Routine cell culture work (e.g passaging, harvesting, counting, assess viability, plating, freezing, thawing)
Maintenance and expansion of mammalian primary cells (e. g. 2D and 3D tumor cell lines, TIL expansion and co-culture systems)
Carrying out flow cytometry experiments and preparation of cell suspensions for sorting
Preparation of single cell or nuclei suspensions for NGS-based single cell sequencing (scRNA-seq, scTCRseq, scATAC-seq) using the 10x Genomics platform
Generation of cDNA and ATAC libraries and preparation for sequencing on the Illumina platforms (MiSeq or NovaSeq 6000)
Performance of functional TCR validation assays (e.g. ELISpot and killing assays)
Training of new employees and writing standard operating procedures (SOPs)
Timely generation of high-quality data and comprehensive documentation and communication of results
A completed professional training as BTA/MTA, biological laboratory assistant, or a Bachelor (B.Sc.)/Master (M.Sc.) degree in natural sciences
Experience in molecular biology techniques (RNA extraction, PCR, NGS library preparation) is required
Experience in mammalian cell culture is essential
Experience in immunological techniques (e.g. ELISA, flow cytometry) would be of advantage
Any practice in processing primary samples (patient material, mouse samples) would be a plus
Strong organizational skills and excellent time management
Very good oral and written communication skills in English and German
Excellent sense of responsibility, attention to details and high reliability are essential
Enthusiasm and curiosity for the diverse activities of our research institute as well as the ability to work in an international team completes your profile.
A dynamic, innovative and creative research environment
An open, collegial and cordial working atmosphere in a respectful corporate culture
Highly interactive working environment across teams
A high degree of diversity in the workforce
Flat hierarchies
Performance-related remuneration and other benefits
The opportunity for personalised further training
Job ticket (Deutschlandticket) incl. employer allowance
Bike leasing (Businessbike)
The opportunity for hybrid working
Process primary samples (healthy donor and patient tissues), including handling of fresh, cryopreserved, or fixed material and tissue dissociation
Routine cell culture work (e.g passaging, harvesting, counting, assess viability, plating, freezing, thawing)
Maintenance and expansion of mammalian primary cells (e. g. 2D and 3D tumor cell lines, TIL expansion and co-culture systems)
Carrying out flow cytometry experiments and preparation of cell suspensions for sorting
Preparation of single cell or nuclei suspensions for NGS-based single cell sequencing (scRNA-seq, scTCRseq, scATAC-seq) using the 10x Genomics platform
Generation of cDNA and ATAC libraries and preparation for sequencing on the Illumina platforms (MiSeq or NovaSeq 6000)
Performance of functional TCR validation assays (e.g. ELISpot and killing assays)
Training of new employees and writing standard operating procedures (SOPs)
Timely generation of high-quality data and comprehensive documentation and communication of results
A completed professional training as BTA/MTA, biological laboratory assistant, or a Bachelor (B.Sc.)/Master (M.Sc.) degree in natural sciences
Experience in molecular biology techniques (RNA extraction, PCR, NGS library preparation) is required
Experience in mammalian cell culture is essential
Experience in immunological techniques (e.g. ELISA, flow cytometry) would be of advantage
Any practice in processing primary samples (patient material, mouse samples) would be a plus
Strong organizational skills and excellent time management
Very good oral and written communication skills in English and German
Excellent sense of responsibility, attention to details and high reliability are essential
Enthusiasm and curiosity for the diverse activities of our research institute as well as the ability to work in an international team completes your profile.
A dynamic, innovative and creative research environment
An open, collegial and cordial working atmosphere in a respectful corporate culture
Highly interactive working environment across teams
A high degree of diversity in the workforce
Flat hierarchies
Performance-related remuneration and other benefits
The opportunity for personalised further training
Job ticket (Deutschlandticket) incl. employer allowance
Bike leasing (Businessbike)
The opportunity for hybrid working
Ref-Nr.: 8265669
Aktualisiert:
16.01.2026
Quelle: Bundesagentur für Arbeit
weitere Infos Rechtliche Hinweise zur Nutzung
Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.
weitere Infos Rechtliche Hinweise zur Nutzung
Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.
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