Universitätsklinikum Schleswig-Holstein
24103 Kiel - Deutschland
Wissenschaftliche/r Mitarbeiter/in
Arbeit
Teilzeit Nachmittag
ab 18.02.2026
Beschreibung
Das Universitätsklinikum Schleswig-Holstein (UKSH) verbindet internationale Spitzenforschung mit interdisziplinärer Krankenversorgung. Wir sind einziger Maximalversorger und größter Arbeitgeber des Landes. Unsere rund 17.000 Mitarbeitenden stellen eine höchst individuelle Versorgung sicher - unverzichtbar für die Menschen in Schleswig-Holstein.
Vacancy: Synthesis of catalysts and small organic molecules for hyperpolarized MRI.
Project description
Hyperpolarization transiently boosts the NMR/MRI... weiter lesen
Vacancy: Synthesis of catalysts and small organic molecules for hyperpolarized MRI.
Project description
Hyperpolarization transiently boosts the NMR/MRI... weiter lesen
Das Universitätsklinikum Schleswig-Holstein (UKSH) verbindet internationale Spitzenforschung mit interdisziplinärer Krankenversorgung. Wir sind einziger Maximalversorger und größter Arbeitgeber des Landes. Unsere rund 17.000 Mitarbeitenden stellen eine höchst individuelle Versorgung sicher - unverzichtbar für die Menschen in Schleswig-Holstein.
Vacancy: Synthesis of catalysts and small organic molecules for hyperpolarized MRI.
Project description
Hyperpolarization transiently boosts the NMR/MRI signal of 13C- tracers by orders of magnitude, enabling real-time, noninvasive metabolic imaging. The motivation is to study disease (e.g. cancer) metabolism. We develop chemical synthesis routes for SABRE and PHIP catalysts and for isotopically labeled small molecules (e.g., vinyl pyruvate) to enable hyperpolarized NMR and MRI. The focus is on organometallic/organic synthesis of hydrogenation catalysts, ligand optimization, and isotope labeling (13C, 2H), followed by rigorous spectroscopic characterization and polarization screening.
Start in our team
We are looking for professional and competent support to start as soon as possible, limited for 3 years (PhD track) or ≥2.5 years (Postdoc track).
What we offer:
* The salary will be based on the German E13 TV-L scale (75%), if terms and conditions under collective bargaining law are fulfilled
* Part-time employment currently 28,75 hours/week
* Access to imaging and chemical facilities of the section of biomedical imaging of Kiel University (PI Prof. Jan-Bernd Hövener).
* An intensive Ph.D. supervision in an interdisciplinary team
* You can find more attractive UKSH benefits here: Benefits (uksh.de)
Your tasks:
* Synthesize SABRE/PHIP catalysts (e.g., Ir- and Rh-based complexes) and tailor ligands
* Design and execute isotope-labeling routes (13C, 2H) for target substrates optimize yields, purity, and scalability
* Characterize compounds by NMR (1D/2D), document structure, purity, and batch reproducibility
* Presenting the results at national and international conferences and publishing results in scientific journals
Your profile:
* Knowledge in NMR/MRI are not prerequisite
* PhD track: Master's degree (or equivalent) in Chemistry or a closely related field with a strong record in synthetic chemistry
* Postdoc track: PhD in Organic/Organometallic Chemistry (or closely related) with demonstrated output in catalyst and/or isotope-labeled molecule synthesis
* Hands-on experience with air/moisture-sensitive techniques (Schlenk, glovebox) and homogeneous catalysis
* Team-oriented, safety-minded, and motivated to translate synthesis into working hyperpolarization methods for NMR/MRI
Please submit your application until 03.03.2026, indicating the reference number 28040.
PI's of the project and contact persons
Prof. Dr. Jan-Bernd Hövener, jan.hoevener@rad.uni-kiel.de
Dr. Andrey Pravdivtsev, andrey.pravdivtsev@rad.uni-kiel.de
Section Biomedical Imaging, Dept. for Radiology and Neuroradiology, UKSH and Kiel University
Vacancy: Synthesis of catalysts and small organic molecules for hyperpolarized MRI.
Project description
Hyperpolarization transiently boosts the NMR/MRI signal of 13C- tracers by orders of magnitude, enabling real-time, noninvasive metabolic imaging. The motivation is to study disease (e.g. cancer) metabolism. We develop chemical synthesis routes for SABRE and PHIP catalysts and for isotopically labeled small molecules (e.g., vinyl pyruvate) to enable hyperpolarized NMR and MRI. The focus is on organometallic/organic synthesis of hydrogenation catalysts, ligand optimization, and isotope labeling (13C, 2H), followed by rigorous spectroscopic characterization and polarization screening.
Start in our team
We are looking for professional and competent support to start as soon as possible, limited for 3 years (PhD track) or ≥2.5 years (Postdoc track).
What we offer:
* The salary will be based on the German E13 TV-L scale (75%), if terms and conditions under collective bargaining law are fulfilled
* Part-time employment currently 28,75 hours/week
* Access to imaging and chemical facilities of the section of biomedical imaging of Kiel University (PI Prof. Jan-Bernd Hövener).
* An intensive Ph.D. supervision in an interdisciplinary team
* You can find more attractive UKSH benefits here: Benefits (uksh.de)
Your tasks:
* Synthesize SABRE/PHIP catalysts (e.g., Ir- and Rh-based complexes) and tailor ligands
* Design and execute isotope-labeling routes (13C, 2H) for target substrates optimize yields, purity, and scalability
* Characterize compounds by NMR (1D/2D), document structure, purity, and batch reproducibility
* Presenting the results at national and international conferences and publishing results in scientific journals
Your profile:
* Knowledge in NMR/MRI are not prerequisite
* PhD track: Master's degree (or equivalent) in Chemistry or a closely related field with a strong record in synthetic chemistry
* Postdoc track: PhD in Organic/Organometallic Chemistry (or closely related) with demonstrated output in catalyst and/or isotope-labeled molecule synthesis
* Hands-on experience with air/moisture-sensitive techniques (Schlenk, glovebox) and homogeneous catalysis
* Team-oriented, safety-minded, and motivated to translate synthesis into working hyperpolarization methods for NMR/MRI
Please submit your application until 03.03.2026, indicating the reference number 28040.
PI's of the project and contact persons
Prof. Dr. Jan-Bernd Hövener, jan.hoevener@rad.uni-kiel.de
Dr. Andrey Pravdivtsev, andrey.pravdivtsev@rad.uni-kiel.de
Section Biomedical Imaging, Dept. for Radiology and Neuroradiology, UKSH and Kiel University
Ref-Nr.: 9413934
Aktualisiert:
25.02.2026
Quelle: Bundesagentur für Arbeit
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Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.
weitere Infos Rechtliche Hinweise zur Nutzung
Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.
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