TRON -Translationale Onkologie an der Universitätsmedizin der JGU Mainz gemeinnützige G...
55131 Mainz am Rhein - Deutschland
Bioinformatiker/in
Arbeit
Vollzeit
ab 09.01.2026
Beschreibung
We seek a highly motivated Computational Scientist (m/f/d) for Cancer Antigen Discovery to join our Computational Genomics unit. We are an interdisciplinary team of scientists, PhD students, and software engineers passionate about developing bioinformatics tools to identify biomarkers and therapeutic targets for personalized immunotherapies against cancer. In close collaboration with other teams at TRON, as well as with partners from academia, clinics, and industry, we apply our computational ap...
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We seek a highly motivated Computational Scientist (m/f/d) for Cancer Antigen Discovery to join our Computational Genomics unit. We are an interdisciplinary team of scientists, PhD students, and software engineers passionate about developing bioinformatics tools to identify biomarkers and therapeutic targets for personalized immunotherapies against cancer. In close collaboration with other teams at TRON, as well as with partners from academia, clinics, and industry, we apply our computational approaches to discover antigen targets and translate them into clinical practice.
The successful candidate will be responsible for identifying and prioritizing novel classes of tumor-specific antigens for personalized mRNA vaccines and other immunotherapies. This will be achieved through the analysis of multi-omics data, using innovative computational approaches supported by validation through molecular and immunological assays.
Computational Scientist - Cancer Antigen Discovery (m/f/d)
Full time - Mainz
Analyze large cohorts of genomic, epigenomic, transcriptomic, and proteomic data to identify and prioritize novel tumor-specific candidate antigen targets.
Develop computational pipelines and models for antigen target detection in individual patients for personalized therapies and recurrent target for off-the-shelf therapies.
Contribute to the design of validation strategies and collaborate on confirming targets through molecular and immunological assays.
Present and discuss in internal meetings, with collaboration partners, and at international conferences.
Writing R&D reports and scientific publications.
Ph.D. in Computational Biology, Immuno-Oncology, or a related data-driven field with at least 2 years of postdoctoral research experience in academia or industry.
Demonstrated scientific expertise in tumor immunology and target discovery for immunotherapies.
Excellent programming skills for reproducible data analysis in Python or R.
Experience analyzing next-generation sequencing (NGS) data.
Hands-on expertise with version control systems (e.g., Git), workflow managers (e.g., Nextflow or Snakemake), databases, and high-performance computing environments.
Experience in leading research projects in a multidisciplinary environment
Enthusiasm and curiosity for the diverse activities of our research institute complete your profile.
A dynamic, innovative and creative research environment
An open, collegial and cordial working atmosphere in a respectful corporate culture
A high degree of diversity in the workforce
Flat hierarchies
Performance-related remuneration and other benefits
The opportunity for personalised further training
Job ticket (Deutschlandticket) incl. employer allowance
Bike leasing (Businessbike)
The opportunity for hybrid working
Access to our GPU-accelerated HPC cluster and laboratories with cutting-edge sequencing technologies and molecular assays
The successful candidate will be responsible for identifying and prioritizing novel classes of tumor-specific antigens for personalized mRNA vaccines and other immunotherapies. This will be achieved through the analysis of multi-omics data, using innovative computational approaches supported by validation through molecular and immunological assays.
Computational Scientist - Cancer Antigen Discovery (m/f/d)
Full time - Mainz
Analyze large cohorts of genomic, epigenomic, transcriptomic, and proteomic data to identify and prioritize novel tumor-specific candidate antigen targets.
Develop computational pipelines and models for antigen target detection in individual patients for personalized therapies and recurrent target for off-the-shelf therapies.
Contribute to the design of validation strategies and collaborate on confirming targets through molecular and immunological assays.
Present and discuss in internal meetings, with collaboration partners, and at international conferences.
Writing R&D reports and scientific publications.
Ph.D. in Computational Biology, Immuno-Oncology, or a related data-driven field with at least 2 years of postdoctoral research experience in academia or industry.
Demonstrated scientific expertise in tumor immunology and target discovery for immunotherapies.
Excellent programming skills for reproducible data analysis in Python or R.
Experience analyzing next-generation sequencing (NGS) data.
Hands-on expertise with version control systems (e.g., Git), workflow managers (e.g., Nextflow or Snakemake), databases, and high-performance computing environments.
Experience in leading research projects in a multidisciplinary environment
Enthusiasm and curiosity for the diverse activities of our research institute complete your profile.
A dynamic, innovative and creative research environment
An open, collegial and cordial working atmosphere in a respectful corporate culture
A high degree of diversity in the workforce
Flat hierarchies
Performance-related remuneration and other benefits
The opportunity for personalised further training
Job ticket (Deutschlandticket) incl. employer allowance
Bike leasing (Businessbike)
The opportunity for hybrid working
Access to our GPU-accelerated HPC cluster and laboratories with cutting-edge sequencing technologies and molecular assays
Ref-Nr.: 8309364
Aktualisiert:
20.01.2026
Quelle: Bundesagentur für Arbeit
weitere Infos Rechtliche Hinweise zur Nutzung
Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.
weitere Infos Rechtliche Hinweise zur Nutzung
Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.
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