Masterand Antibody-Mediated PROTAC Drug Delivery (all genders)

Merck KGaA

64293 Darmstadt - Deutschland

Ingenieur/in - Biotechnologie Arbeit Vollzeit ab 26.05.2026

Beschreibung

Work Your Magic with us&excl;&NewLine;&NewLine;&NewLine;Ready to explore, break barriers, and discover more&quest; We know you’ve got big plans – so do we&excl; Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics&period; Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet&per... weiter lesen

Work Your Magic with us! Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe. About the Team You will become part of a highly motivated team of scientists working at the exciting interface of platform technology development, drug design, and lead candidate nomination. Our team is pioneering a novel, antibody-mediated drug delivery platform specifically tailored for PROTACs (Proteolysis Targeting Chimeras): the PROxAb Shuttle. Project Description The central goal of this master thesis is to derive parameters to predict suitability of a PROTAC-antibody pair for treating a given oncology indication. You will systematically screen different PROTAC–antibody combinations on multiple cell lines using cellular assays in a direct-to-biology manner to establish clear selection criteria and structure–activity relationships. Additionally, you will use AI-based tools to handle, analyze, and extract meaningful trends from the large datasets generated. Your Responsibilities - Design, implement, and analyze cell viability assay experiments to assess PROTAC–antibody combinations - Conduct systematic screenings to define payload selection criteria - Apply AI and data science approaches to process and interpret large experimental datasets to identify trends and derive conclusions - Present your findings clearly and confidently to a scientific audience Your Profile - Currently enrolled in a Master’s program in Biotechnology, Biochemistry, Biomedical Sciences, Molecular Medicine, or Medicinal Chemistry - Independent and thorough working mode with a strong sense of scientific rigor - Confidence in structuring and presenting scientific concepts - Excellent English and fluency in German is mandatory Join us and contribute to shaping next-generation targeted therapies. What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Ref-Nr.: 11166038

Aktualisiert: 25.05.2026

Quelle: Bundesagentur für Arbeit
weitere Infos Rechtliche Hinweise zur Nutzung
Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.

Passende Jobvorschläge
Basierend auf Beruf und Standort

Jobs als Ingenieur/in - Biotechnologie in Darmstadt Jobs als Ingenieur/in - Biotechnologie Alle Jobs in Darmstadt

Passende Jobs für dich

Ingenieur / Techniker hardwarenaher Softwaretest / Validation Engineer (m/w/d)

Brunel

97072 Würzburg

Arbeit ab 27.05.2026

Mitarbeiter Technologietransfer und Prozessdesign (m/w/d)

PSM GmbH

66578 Schiffweiler

Arbeit ab 02.04.2026

Senior Quality Specialist (M/W/D)

Persoplan Gesellschaft für Personaldienstleistungen mbH

35041 Marburg

ab 29.04.2026

Senior Quality Partner (m/w/d) – Quality Assurance

Roche Diagnostics GmbH

71636 Ludwigsburg, Württemberg

ab 09.04.2026

Manufacturing Unit Head (m/w/d) PS4

Roche Diagnostics GmbH

82377 Penzberg

Arbeit ab 06.05.2026

Weitere passende Jobs anzeigen