Universitätsklinikum Düsseldorf
40225 Düsseldorf - Deutschland
Biologe/Biologin
Arbeit
Vollzeit
ab 17.03.2026
Beschreibung
The Department of Pediatric Oncology, Hematology and Clinical Immunology at the University Hospital Düsseldorf (UKD) is offering a PhD student position within our research group, which is dedicated to developing novel, individualized drug targets and therapies for high-risk childhood leukemia. While event-free survival for childhood Acute Lymphoblastic Leukemia (ALL) has improved to over 80% in the last decade, specific high-risk subgroups still face a dismal prognosis. To address this, we are i...
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The Department of Pediatric Oncology, Hematology and Clinical Immunology at the University Hospital Düsseldorf (UKD) is offering a PhD student position within our research group, which is dedicated to developing novel, individualized drug targets and therapies for high-risk childhood leukemia. While event-free survival for childhood Acute Lymphoblastic Leukemia (ALL) has improved to over 80% in the last decade, specific high-risk subgroups still face a dismal prognosis. To address this, we are investigating novel precision compounds and synergistic drug combinations, including clinically used drugs, to overcome drug resistance and target oncogene stabilization (Vogt et al. Cell Death Dis 14, 799 (2023)).
We are looking for a highly motivated and team-oriented
PhD Student (m/f/d)
to join our research group on 'Novel Targeted Therapies for Resistant Childhood Acute Leukemia'.
Planning and execution of molecular biological experiments using leukemia cell lines and primary patient-derived cells
Performing advanced Protein Analysis techniques (Western Blotting, Flow Cytometry)
RNA Analysis (qPCR, RNA sequencing)
Drug Screening of therapeutic compounds to identify novel vulnerabilities
Genetic Engineering: Utilizing cutting-edge technologies, including CRISPR/Cas9 genome editing, viral transduction, and nucleofection
In Vivo Research: Designing and performing experiments with mouse models to study leukemia progression and treatment response
A Master’s degree in biology or a related field
Proven experience with in vivo (mouse) models and a FELASA B certification are required
Extensive hands-on experience in laboratory work, utilizing a broad spectrum of methods in biochemistry, molecular biology, and cell biology
Strong analytical skills with the ability to design experiments, interpret complex data sets, and work independently
A highly motivated and communicative atmosphere within a successful translational research group, offering access to core facilities and opportunities to present your research at international conferences.
A thorough introduction to the skills needed, accompanied by supervision and guidance
An initial 2-year contract with the possibility of an extension for the duration of the PhD
Salary according to the German public service scale (TV-L E13, 65%)
We are looking for a highly motivated and team-oriented
PhD Student (m/f/d)
to join our research group on 'Novel Targeted Therapies for Resistant Childhood Acute Leukemia'.
Planning and execution of molecular biological experiments using leukemia cell lines and primary patient-derived cells
Performing advanced Protein Analysis techniques (Western Blotting, Flow Cytometry)
RNA Analysis (qPCR, RNA sequencing)
Drug Screening of therapeutic compounds to identify novel vulnerabilities
Genetic Engineering: Utilizing cutting-edge technologies, including CRISPR/Cas9 genome editing, viral transduction, and nucleofection
In Vivo Research: Designing and performing experiments with mouse models to study leukemia progression and treatment response
A Master’s degree in biology or a related field
Proven experience with in vivo (mouse) models and a FELASA B certification are required
Extensive hands-on experience in laboratory work, utilizing a broad spectrum of methods in biochemistry, molecular biology, and cell biology
Strong analytical skills with the ability to design experiments, interpret complex data sets, and work independently
A highly motivated and communicative atmosphere within a successful translational research group, offering access to core facilities and opportunities to present your research at international conferences.
A thorough introduction to the skills needed, accompanied by supervision and guidance
An initial 2-year contract with the possibility of an extension for the duration of the PhD
Salary according to the German public service scale (TV-L E13, 65%)
Ref-Nr.: 10014945
Aktualisiert:
22.03.2026
Quelle: Bundesagentur für Arbeit
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Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.
weitere Infos Rechtliche Hinweise zur Nutzung
Ob die Stelle noch verfügbar ist und weitere Informationen findest du direkt auf der Website der Bundesagentur für Arbeit. Bitte beachte: OPROMA ist nicht der Anbieter dieser Stelle und kann keine Auskünfte geben.
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